Karuna Yoga Vidya Peetham Bangalore

Neuromuscular junction (Myoneural junction)

A neuromuscular junction is a synapse between a motor neuron and skeletal muscle. The space between the motor neuron and the skeletal muscle cell is simply referred to as a synapse. Synaptic transmission includes all the events within the synapse leading to excitation of the muscle. At this site, the nerve loses its myelin sheath and gets expanded. Acetylcholine is stored in some vesicles present in this expanded portion. Motor end plate is the part of the muscle facing the expanded nerve terminal.

The neuron is sending the transmission and is thus referred to as the pre-synaptic cell, while the muscle is receiving the transmission and is referred to as the post-synaptic cell. Neurotransmitters are molecules stored in the pre-synaptic cell that is secreted into the synapse. Neurotransmitters, in turn, bind to receptors on the postsynaptic cell membrane, and these receptors are specific for that neurotransmitter. The structure motor end plates convoluted and it has enzyme acetyl cholinesterase.

 

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